Professor Nic Peter Smith

BE(Hons), PhD

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Dean of Engineering


Prior to joining the Faculty of Engineering in August 2013, Nic Smith was Head of Biomedical Engineering at Kings College, London and before that Professor of Computational Physiology at the University Computing Laboratory, University of Oxford. He is a Honorary Consultant at Guys and St Thomas' Hospital London and a Fellow of the Newton Institute University of Cambridge. 

Professor Smith leads a computational modelling group which is currently a central contributor to the European based Virtual Physiological Human (VPH) Project. He has authored over 150 peer reviewed journal publications, 300 conference publications and is on the editorial board for the international peer review journals including the Journal of Physiology, Microcirculation, Medical & Biological Engineering & Computing and International journal of Computational Methods in Bioengineering. He is the lead-author on several patent applications filed with the United States and European Patent Offices, which outline intellectual property covering the development of anatomically based physiological models and specific applications.

Research | Current

Professor Smith's research is characterised by the development of integrated multi-scale and multi-physics models, which provide the ability to link biophysically detailed experimental data to integrated function from sub-cellular to the whole organ level. Within the scope of this work, he has developed computational techniques to enable specific model developments that have in turn been applied to provide insight into both basic physiology and clinical contexts. This research is focused on electrophysiology and contraction at the cellular level and the multi-scale translation of these models to simulate blood flow and cardiac electro-mechanics at the tissue level.

Selected publications and creative works (Research Outputs)

  • Hunter, P. J., & Smith, N. P. (2016). The Cardiac Physiome Project. The Journal of Physiology, 594 (23), 6815-6816. 10.1113/JP273415
    Other University of Auckland co-authors: Peter Hunter
  • Niederer, S. A., & Smith, N. P. (2016). Using physiologically based models for clinical translation: predictive modelling, data interpretation or something in-between?. The Journal of Physiology, 594 (23), 6849-6863. 10.1113/JP272003
  • Lee, P., Carlson, B. E., Chesler, N., Olufsen, M. S., Qureshi, M. U., Smith, N. P., ... Beard, D. A. (2016). Heterogeneous mechanics of the mouse pulmonary arterial network. Biomechanics and modeling in mechanobiology, 15 (5), 1245-1261. 10.1007/s10237-015-0757-y
  • Rivolo, S., Hadjilucas, L., Sinclair, M., van Horssen, P., van den Wijngaard, J., Wesolowski, R., ... Lee, J. (2016). Impact of coronary bifurcation morphology on wave propagation. American Journal of Physiology - Heart and Circulatory Physiology, 311 (4), H855-H870. 10.1152/ajpheart.00130.2016
  • Fovargue, L., Rivolo, S., Webb, J., Claridge, S., Patterson, T., Giffard-Roisin, S., ... Nordsletten, D. (2016). Non-invasive prediction of acute hemodynamics in cardiac resynchronisation therapy through patient specific modeling. Paper presented at Congress of the European-Society-of-Cardiology (ESC), Rome, ITALY. 27 August - 31 August 2016. EUROPEAN HEART JOURNAL. (pp. 1).
  • Gattoni, S., Røe ÅT, Frisk, M., Louch, W. E., Niederer, S. A., & Smith, N. P. (2016). The calcium-frequency response in the rat ventricular myocyte: an experimental and modelling study. The Journal of Physiology, 594 (15), 4193-4224. 10.1113/JP272011
  • Crozier, A., Blazevic, B., Lamata, P., Plank, G., Ginks, M., Duckett, S., ... Razavi, R. (2016). The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study. Journal of molecular and cellular cardiology, 96, 93-100. 10.1016/j.yjmcc.2015.10.026
  • Lee, J., Cookson, A., Roy, I., Kerfoot, E., Asner, L., Vigueras, G., ... Smith, N. P. (2016). Multiphysics Computational Modeling in $\boldsymbol{\mathcal{C}}\mathbf{Heart}$. SIAM Journal on Scientific Computing, 38 (3), C150-C178. 10.1137/15M1014097


Contact details

Primary location

Level 5, Room 509
New Zealand

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